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Table 4 Gender distribution of HOMA-IR cut-off levels, with their corresponding sensitivity and specificity,for classify of IDF MetS and ATPIII MetS, in diabetic and non-diabetic individuals

From: Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study

IDF criteria

Population

Criterion of specificity = 0.7

Youden index criterion

 

Cut point

Sensitivity

Specificity

Cut point

Sensitivity

Specificity

 Diabetic

      

Men

1.55

0.60

0.70

1.60

0.59

0.74

Women

2.22

0.37

0.70

1.58

0.68

0.46

Non-diabetic

      

Men

2.25

0.57

0.70

2.05

0.65

0.64

Women*

      

 30 years

2.11

0.77

0.70

2.31

0.71

0.76

 50 years

2.05

0.69

0.70

2.05

0.69

0.70

 70 years

2.38

0.45

0.70

2.53

0.40

0.75

ATP III criteria

Population

Criterion of specificity = 0.7

Youden index criterion

 

Cut point

Sensitivity

Specificity

Cut point

Sensitivity

Specificity

 Diabetic

      

Men

1.57

0.64

0.70

1.60

0.63

0.73

Women

2.22

0.37

0.70

1.58

0.68

0.46

Non-diabetic

      

Men

2.27

0.61

0.70

1.85

0.78

0.57

Women*

      

 30 years

2.12

0.79

0.70

2.36

0.73

0.77

 50 years

2.05

0.73

0.70

2.07

0.72

0.71

 70 years

2.37

0.48

0.70

2.47

0.44

0.74

  1. *In non-diabetic females HOMA-IR cut-off values are estimated for 30, 50, and 70 years of age, because there is a non linear effect of age on test performance to classify IDF-defined MetS (P value < 0.001) and ATP III-defined MetS (P value = 0.012).
  2. HOMA-IR, homeostasis model assessment of IR; ATPIII, Third Adult Treatment Panel; IDF, International Diabetes Federation; MetS, Metabolic Syndrome.
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BMC Endocrine Disorders

ISSN: 1472-6823

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