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  1. Vitamin D deficiency is diagnosed by total serum 25-hydroxyvitamin D (25(OH)D) concentration and is associated with poor health and increased mortality; however, some populations have low 25(OH) D concentratio...

    Authors: Lina H. M. Ahmed, Alexandra E. Butler, Soha R. Dargham, Aishah Latif, Omar M. Chidiac, Stephen L. Atkin and Charbel Abi Khalil

    Citation: BMC Endocrine Disorders 2020 20:161

    Content type: Research article

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  2. Dietary fatty acids are important dietary determinants of metabolic disorders in human. However, it is important to develop an index that considers not only the amount of dietary fatty acids but also the struc...

    Authors: Nika Soltani, Mahdieh Abbasalizad Farhangi, Leila Nikniaz and Mahsa Mahmoudinezhad

    Citation: BMC Endocrine Disorders 2020 20:159

    Content type: Research article

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  3. A growing body of evidence supports neutrophils as having an active role in the development of diabetic kidney disease (DKD). However, the clinical relevance of neutrophils and DKD in autoimmune diabetes remai...

    Authors: Yao Yu, Qiuqiu Lin, Dewei Ye, Yanfei Wang, Binbin He, Yanhua Li, Gan Huang, Zhiguang Zhou and Yang Xiao

    Citation: BMC Endocrine Disorders 2020 20:158

    Content type: Research article

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  4. Follow-up care provided via telemedicine (TM) is intended to be a more integrated care pathway to manage diabetes-related foot ulcers (DFU) than traditionally-delivered healthcare. However, knowledge of the ef...

    Authors: Marjolein M. Iversen, Jannicke Igland, Hilde Smith-Strøm, Truls Østbye, Grethe S. Tell, Svein Skeie, John G. Cooper, Mark Peyrot and Marit Graue

    Citation: BMC Endocrine Disorders 2020 20:157

    Content type: Research article

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  5. Previous studies have suggested that patients with diabetes mellitus (DM) have higher prevalence of atherosclerotic cardiovascular disease (ASCVD), and plasma levels of free fatty acids (FFAs) are a useful mar...

    Authors: Ming-Hua Zhang, Ye-Xuan Cao, Li-Guo Wu, Na Guo, Bing-Jie Hou, Li-Jing Sun, Yuan-Lin Guo, Na-Qiong Wu, Qian Dong and Jian-Jun Li

    Citation: BMC Endocrine Disorders 2020 20:156

    Content type: Research article

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  6. Detailed description of hyperglycemia management in diabetic patients infected with SARS-CoV-2 remain limited, although patients with diabetes show higher complication and mortality rate than patients without ...

    Authors: François R. Jornayvaz, Benjamin Assouline, Jérôme Pugin and Karim Gariani

    Citation: BMC Endocrine Disorders 2020 20:155

    Content type: Case report

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  7. Glucocorticoid therapy is the most common cause of iatrogenic osteoporosis. Less is known regarding the effect of glucocorticoids when used as replacement therapy on bone remodelling in patients with adrenal i...

    Authors: Rosemary Dineen, Lucy-Ann Behan, Grainne Kelleher, Mark J. Hannon, Jennifer J. Brady, Bairbre Rogers, Brian G. Keevil, William Tormey, Diarmuid Smith, Christopher J. Thompson, Malachi J. McKenna, Wiebke Arlt, Paul M. Stewart, Amar Agha and Mark Sherlock

    Citation: BMC Endocrine Disorders 2020 20:154

    Content type: Research article

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  8. The objectives of this study were to estimate the prevalence of microalbuminuria and examine the association of microalbuminuria with metabolic syndrome (MetS) and its component in a Bangladeshi adult cohort.

    Authors: Muntakim Mahmud Saadi, Manindra Nath Roy, Rubena Haque, Farida Akhter Tania, Shakil Mahmood and Nurshad Ali

    Citation: BMC Endocrine Disorders 2020 20:153

    Content type: Research article

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  9. Metabolic inflammation is an essential event in obesity-induced diabetes and insulin resistance. In obesity, an increasing number of macrophages recruited into visceral adipose tissues undergo significant M1-like...

    Authors: Chaolong Liu, Yanting Yuan, Ji Zhou, Ruixin Hu, Lixia Ji and Guohui Jiang

    Citation: BMC Endocrine Disorders 2020 20:152

    Content type: Research article

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  10. Low dose naltrexone (LDN) is reported to have beneficial effects in several autoimmune diseases. The purpose of this study was to examine whether starting LDN was followed by changes in the dispensing of thyro...

    Authors: Guttorm Raknes and Lars Småbrekke

    Citation: BMC Endocrine Disorders 2020 20:151

    Content type: Research article

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  11. Despite the evidence available on the adverse impact of gestational diabetes (GDM) and thyroid disorders on developing type 2 diabetes (T2DM), the concurrent influence of these disorders on the incidence of T2...

    Authors: Maryam Zahedi, Elham Kazemian, Fahimeh Ramezani-Tehrani, Maryam Tohidi, Fereidoun Azizi, Davood Khalili, Maryam Rahmati and Atieh Amouzegar

    Citation: BMC Endocrine Disorders 2020 20:150

    Content type: Research article

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  12. A high-molecular-weight form of insulin-like growth factor-2 (IGF-2), known as “big” IGF-2, is occasionally produced by various tumor types, leading to hypoglycemia. Although solitary fibrous tumor (SFT) is a ...

    Authors: Keizo Kaneko, Shojiro Sawada, Chihiro Satake, Keiichi Kondo, Tomohito Izumi, Mamiko Tanaka, Junta Imai, Tetsuya Yamada, Hiroki Katsushima, Fumiyoshi Fujishima and Hideki Katagiri

    Citation: BMC Endocrine Disorders 2020 20:148

    Content type: Case report

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  13. Worldwide, the epidemiological and demographic transitions have resulted in nutrition shift characterized by an increased consumption of high energy fast food products. In just over 3 decades, overweight and o...

    Authors: Pedro Pallangyo, Zabella S. Mkojera, Naairah R. Hemed, Happiness J. Swai, Nsajigwa Misidai, Lucy Mgopa, Smita Bhalia, Jalack Millinga, Theophil L. Mushi, Lucia Kabeya, Aisha Omar, Alice Kaijage, Rydiness Mulashani, Silvia Mosha, Faustina Mwapinga and Mohamed Janabi

    Citation: BMC Endocrine Disorders 2020 20:147

    Content type: Research article

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  14. The risk of surgical site infection has been reported to be higher in patients with poorly controlled diabetes. Since chronic hyperglycemia impairs neutrophil functions, preoperative glycemic control may resto...

    Authors: Daichi Fujimoto, Yuki Nomura, Moritoki Egi, Norihiko Obata and Satoshi Mizobuchi

    Citation: BMC Endocrine Disorders 2020 20:146

    Content type: Research article

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  15. This study tested the association between serum levels of microRNA-486, −146b and -15b and betatrophin in normal and obese children with/without type 2 diabetes mellitus (T2DM).

    Authors: Khalid M. Mohany, Osamah Al rugaie, Osama Al-wutayd, Abdullah Al-Nafeesah and Tahia H. Saleem

    Citation: BMC Endocrine Disorders 2020 20:145

    Content type: Research article

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  16. Congenital adrenal hyperplasia (CAH) with 17α-hydroxylase deficiency is a rare disease; patients often require lifetime cortisol treatment. In this case report, we presented a patient with CAH and 17α-hydroxyl...

    Authors: Chenyu Xiang, Minmin Han, Yi Zhang, Jianhong Yin, Li’e Pei, Jing Yang and Yunfeng Liu

    Citation: BMC Endocrine Disorders 2020 20:144

    Content type: Case report

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  17. Previous studies have shown inconsistent results about the usefulness of bilateral inferior petrosal sinus sampling (BIPSS) in differential diagnosis of adrenocorticotropic hormone (ACTH)-dependent Cushing syn...

    Authors: Hao Wang, Ying Ba, Qian Xing and Run-Ce Cai

    Citation: BMC Endocrine Disorders 2020 20:143

    Content type: Research article

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  18. Primary Empty Sella (PES) syndrome is an increasingly common disorder, mostly diagnosed as an incidental finding during brain imaging scans. We intended to review the clinical management and hormonal profile o...

    Authors: Aishah A. Ekhzaimy, Muhammad Mujammami, Shabana Tharkar, Manahel A. Alansary and Daad Al Otaibi

    Citation: BMC Endocrine Disorders 2020 20:142

    Content type: Research article

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  19. Studies have shown that the response of bone mineral density (BMD) to parathyroidectomy for symptomatic primary hyperparathyroidism (PHPT) is heterogeneous and difficult to predict. However, the independent fa...

    Authors: Shuai Lu, Maoqi Gong, Yejun Zha, Aimin Cui, Chen Chen, Weitong Sun, Kehan Hua, Wei Tian and Xieyuan Jiang

    Citation: BMC Endocrine Disorders 2020 20:141

    Content type: Research article

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  20. The infants born to women who are overweight or obese in pregnancy are at an increased risk of being born macrosomic or large for gestational age. Antenatal dietary and lifestyle interventions have been shown ...

    Authors: Amanda J. Poprzeczny, Jennie Louise, Andrea R. Deussen and Jodie M. Dodd

    Citation: BMC Endocrine Disorders 2020 20:139

    Content type: Research article

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  21. Plasma renin activity (PRA) is generally increased in patients with pheochromocytoma (PCC) due to low circulating plasma volume and activation of β-1 adrenergic receptor signaling. However, there has been no s...

    Authors: Tomoko Yamada, Hidenori Fukuoka, Yusei Hosokawa, Yukiko Odake, Kenichi Yoshida, Ryusaku Matsumoto, Hironori Bando, Yuko Okada, Yushi Hirota, Genzo Iguchi, Wataru Ogawa and Yutaka Takahashi

    Citation: BMC Endocrine Disorders 2020 20:140

    Content type: Research article

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  22. The specific underlying pathogenesis of prolactinoma has not been clarified yet, to the best of our knowledge. p38 mitogen-activated protein kinase (MAPK) signaling including p38α MAPK (MAPK14), p38β (MAPK11),...

    Authors: Qiao-yan Ding, Yu Zhang, Li Ma, Yong-gang Chen, Jin-hu Wu, Hong-feng Zhang and Xiong Wang

    Citation: BMC Endocrine Disorders 2020 20:138

    Content type: Research article

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  23. Diabetes is a serious chronic disease. Medical treatment and good psychosocial support are needed to cope with acute and long-term effects of diabetes. Self-management is a large part of diabetes management, w...

    Authors: Elisabet Nerpin, Eva Toft, Johan Fischier, Anna Lindholm-Olinder and Janeth Leksell

    Citation: BMC Endocrine Disorders 2020 20:137

    Content type: Study protocol

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  24. Previous studies have shown the negative impact of sleep disturbances, specifically insomnia symptoms, on glucose metabolism for people with type 2 diabetes (T2D). People with insomnia symptoms are at risk of ...

    Authors: Mohammed M. Alshehri, Shaima A. Alothman, Aqeel M. Alenazi, Jason L. Rucker, Milind A. Phadnis, John M. Miles, Catherine F. Siengsukon and Patricia M. Kluding

    Citation: BMC Endocrine Disorders 2020 20:136

    Content type: Research article

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  25. Euthyroid sick syndrome (ESS) frequently arises in children admitted with diabetic ketoacidosis/diabetic ketosis (DKA/DK). This study evaluates the interplay of various metabolic factors with occurrence of der...

    Authors: Peng Shao, Shujuan Guo, Guimei Li, Daogang Qin, Sen Li and Ying Luan

    Citation: BMC Endocrine Disorders 2020 20:135

    Content type: Research article

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  26. Diabetic foot ulcers (DFU) are associated with high morbidity and mortality globally. Mortality in patients hospitalized for DFU in Nigeria is unacceptably high. This study was undertaken to determine factors ...

    Authors: Olufunmilayo O. Adeleye, Ejiofor T. Ugwu, Ibrahim D. Gezawa, Innocent Okpe, Ignatius Ezeani and Marcelina Enamino

    Citation: BMC Endocrine Disorders 2020 20:134

    Content type: Research article

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  27. Graves’ disease is the commonest cause of thyrotoxicosis whilst thyrotropin (TSH)-producing pituitary adenomas (thyrotropinomas, TSHomas) are very rare and account for just 1–2% of all pituitary adenomas. Coex...

    Authors: Mark Quinn, Waiel Bashari, Diarmuid Smith, Mark Gurnell and Amar Agha

    Citation: BMC Endocrine Disorders 2020 20:133

    Content type: Case report

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  28. Immune checkpoint inhibitors (ICIs) can induce immune-related adverse events (irAEs) including thyroid dysfunction. There are only a few reports on Graves’ disease induced by ICIs. We report a case of new-onse...

    Authors: Hiroshi Yamada, Fumitaka Okajima, Takeshi Onda, Shunji Fujimori, Naoya Emoto and Hitoshi Sugihara

    Citation: BMC Endocrine Disorders 2020 20:132

    Content type: Case report

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  29. Sympathetic activity and insulin resistance have recently been linked with chronic tendon and musculoskeletal pain. Polycystic ovarian syndrome is linked with insulin resistance and increased sympathetic drive...

    Authors: Jacob Jewson, Elisabeth Lambert, Carolina Sari, Eveline Jona, Soulmaz Shorakae, Gavin Lambert and Jamie Gaida

    Citation: BMC Endocrine Disorders 2020 20:131

    Content type: Research article

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  30. Although important achievements have been done in type 2 diabetes mellitus (T2D) treatment and glycemic control, new strategies may take advantage of non-pharmacological approaches and of other potential deter...

    Authors: Rubén Silva-Tinoco, Teresa Cuatecontzi-Xochitiotzi, Viridiana De la Torre-Saldaña, Enrique León-García, Javier Serna-Alvarado, Arturo Orea-Tejeda, Lilia Castillo-Martínez, Juan G. Gay, David Cantú-de-León and Diddier Prada

    Citation: BMC Endocrine Disorders 2020 20:130

    Content type: Research article

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  31. Diabetic foot is an underestimated and redoubtable diabetes complication. The aims of our study were to assess diabetic foot ulcer risk factors according to International Working Group on the Diabetic Foot (IW...

    Authors: B. Zantour, S. Bouchareb, Z. El Ati, F. Boubaker, W. Alaya, W. Kossomtini and M. H. Sfar

    Citation: BMC Endocrine Disorders 2020 20:128

    Content type: Research article

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  32. Fulminant type 1 diabetes mellitus (FT1D) is a newly established subtype of type 1 diabetes. Its etiology has not been fully elucidated. Several cases with FT1D have exhibited pancreatitis or myocarditis.

    Authors: Fujiko Egashira, Midori Kawashima, Ai Morikawa, Minami Kosuda, Hisamitsu Ishihara and Kentaro Watanabe

    Citation: BMC Endocrine Disorders 2020 20:127

    Content type: Case report

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  33. Acromegaly is a rare, chronic and severe disease. Drug therapy including somatostatin analogues (SAs), dopamine receptor agonists and growth hormone receptor antagonists (pegvisomant, PEG) are commonly used to...

    Authors: Lingyun Ma, Daohuang Luo, Ting Yang, Songtao Wu, Min Li, Chaoyang Chen, Shuang Zhou, Lingyue Ma, Ye Wu, Ying Zhou and Yimin Cui

    Citation: BMC Endocrine Disorders 2020 20:126

    Content type: Research article

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  34. Diabetes is a leading cause of Medicare spending; predicting which individuals are likely to be costly is essential for targeting interventions. Current approaches generally focus on composite measures, short ...

    Authors: Julie C. Lauffenburger, Mufaddal Mahesri and Niteesh K. Choudhry

    Citation: BMC Endocrine Disorders 2020 20:125

    Content type: Research article

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  35. Modern imaging plays a central role in the care of obese patients, and there is an integral focus on its use and accessibility in individuals who have alterations of various in various organs. The objective in...

    Authors: Alejandra Martínez Coria, Norma Angélica Estrada-Cruz, María Inés Pérez Ordoñez, Daniel H. Montes-Cortes and Leticia Manuel-Apolinar

    Citation: BMC Endocrine Disorders 2020 20:124

    Content type: Research article

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  36. Type 1 Diabetes (T1D) is a T cell-mediated autoimmune disorder caused by the destruction of insulin-secreting cells. B7-H3 (CD276) plays a vital role in T cell response. However, B7-H3 expression and its clini...

    Authors: Sisi Ding, Yimei Shan, Lili Sun, Sicheng Li, Rong Jiang, Xin Chang, Ziyi Huang, Jing Sun, Cuiping Liu, Chen Fang and Xueguang Zhang

    Citation: BMC Endocrine Disorders 2020 20:123

    Content type: Research article

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  37. The prevalence of type 2 diabetes mellitus (T2DM) is expected to increase from 7.7% in 2017 to 8.4% in 2045 worldwide. Diabetes complications contribute to morbidity and mortality. To evaluate whether the diab...

    Authors: Hyunju Yoo, Eunjung Choo and Sukhyang Lee

    Citation: BMC Endocrine Disorders 2020 20:122

    Content type: Research article

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  38. The association between the polymorphisms in the vitamin D receptor (VDR) gene and the risk of type 1 diabetes mellitus (T1DM) has been evaluated in several studies. However, the findings were inconclusive. Thus,...

    Authors: Na Zhai, Ramtin Bidares, Masoud Hassanzadeh Makoui, Saeed Aslani, Payam Mohammadi, Bahman Razi, Danyal Imani, Mohammad Yazdchi and Haleh Mikaeili

    Citation: BMC Endocrine Disorders 2020 20:121

    Content type: Research article

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  39. Basedow’s disease and Hashimoto’s thyroiditis are autoimmune thyroid disorders and usually diagnosed with elevation of serum autoimmune antibodies. Thyrotropin receptor antibodies (TRAb) and/or thyroid-stimula...

    Authors: Megumi Horiya, Takatoshi Anno, Fumiko Kawasaki, Yuichiro Iwamoto, Shintaro Irie, Yasumasa Monobe, Koichi Tomoda, Kohei Kaku, Shuhei Nakanishi and Hideaki Kaneto

    Citation: BMC Endocrine Disorders 2020 20:120

    Content type: Case report

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  40. The growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis is critical for the regulation of children’s growth and development. Serum IGF-1 concentrations are usually low in individuals with idiopathic sh...

    Authors: Qianqian Zhao, Mei Zhang, Baolan Ji, Yuntian Chu, Hui Pan, Wenhua Yan and Bo Ban

    Citation: BMC Endocrine Disorders 2020 20:119

    Content type: Research article

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  41. The escalating prevalence of adrenal incidentaloma (AI) has been associated with the improvement of radiologic techniques and widespread imaging in aging population. It is currently unclear whether patients wi...

    Authors: Ana Podbregar, Andrej Janez, Katja Goricar and Mojca Jensterle

    Citation: BMC Endocrine Disorders 2020 20:118

    Content type: Research article

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  42. Acromegaly patients managed on Somatostatin receptor ligands (SRLs), the most common first-line pharmacotherapy for acromegaly, may still experience acromegaly symptoms such as headache, sweating, fatigue, sof...

    Authors: Eliza B. Geer, Jill Sisco, Daphne T. Adelman, William H. Ludlam, Asi Haviv, Shuqian Liu, Susan D. Mathias, Dana Gelbaum and Lizheng Shi

    Citation: BMC Endocrine Disorders 2020 20:117

    Content type: Research article

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  43. Cushing’s syndrome has been described as a complex endocrine disorder characterized with high cortisol concentration. Correct and early diagnosis of Cushing’s syndrome is challenging. According to the latest g...

    Authors: Huiwen Tan, Dawei Chen, Yerong Yu, Kai Yu, Weiming He, Bowen Cai, Su Jiang, Ying Tang, Nanwei Tong and Zhenmei An

    Citation: BMC Endocrine Disorders 2020 20:116

    Content type: Case report

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  44. Primary aldosteronism (PA) increases the risk of cardiovascular morbidity, including stroke, coronary artery disease, atrial fibrillation, and heart failure. The relationship between primary aldosteronism and ...

    Authors: Ying Zhang, Fang Luo, Peng Fan, Xu Meng, Kunqi Yang and Xianliang Zhou

    Citation: BMC Endocrine Disorders 2020 20:115

    Content type: Case report

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  45. We investigated whether the contralateral suppression index in aldosterone-producing adrenal adenoma could be used as a diagnostic criterion when catheterization in either right or left adrenal vein fails or w...

    Authors: Jeongmin Lee, Borami Kang, Jeonghoon Ha, Min-Hee Kim, Byungil Choi, Tae-Ho Hong, Moo IL Kang and Dong-Jun Lim

    Citation: BMC Endocrine Disorders 2020 20:114

    Content type: Research article

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  46. Colorectal cancer (CRC), which is related with insulin resistance, is a one of the most common cancers. Triglyceride-glucose index (TyG index) was made for a marker of insulin resistance. We conducted the inve...

    Authors: Takuro Okamura, Yoshitaka Hashimoto, Masahide Hamaguchi, Akihiro Obora, Takao Kojima and Michiaki Fukui

    Citation: BMC Endocrine Disorders 2020 20:113

    Content type: Research article

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