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Table 4 Risk of having metabolic syndrome according to quartiles of thyroid hormone parameters, in men

From: Thyroid function and metabolic syndrome in the population-based LifeLines cohort study

 

Quartile

MetS/Total, n (%)

model 1

model 2

model 3

model 4

TSH

1

578/2923 (19.8)

1

1

1

1

2

595/2975 (20.0)

1.014 (0.893–1.153)

1.015 (0.892–1.155)

1.030 (0.904–1.174)

1.000 (0.861–1.161)

3

618 (2946 (21.0)

1.077 (0.948–1.223)

1.072 (0.943–1.219)

1.116 (0.980–1.271)

1.101 (0.949–1.276)

4

650/2975 (21.8)

1.134 (1.000–1.286)

1.110 (0.977–1.261)

1.155 (1.015–1.314)

1.214 (1.047–1.407)

FT4

1

796/2877 (27.7)

1

1

1

1

2

635/3000 (21.2)

0.702 (0.623–0.791) #

0.717 (0.635–0.809) #

0.704 (0.623–0.796) #

0.816 (0.709–0.939) #

3

532/3014 (17.7)

0.560 (0.495–0.635) #

0.596 (0.525–0.675) #

0.579 (0.509–0.657) #

0.733 (0.634–0.848) #

4

478/2928 (16.3)

0.510 (0.449–0.579) #

0.567 (0.498–0.646) #

0.545 (0.478–0.622) #

0.722 (0.621–0.839) #

FT3

1

516/2655 (19.4)

1

1

1

1

2

652/3300 (19.8)

1.021 (0.897–1.161)

1.192 (1.045–1.360)

1.172 (1.026–1.339) #

1.174 (1.010–1.366)

3

695/3185 (21.8)

1.157 (1.018–1.315)

1.487 (1.302–1.699) #

1.458 (1.275–1.668) #

1.360 (1.167–1.586) #

4

578/2679 (21.6)

1.140 (0.998–1.303)

1.652 (1.434–1.904) #

1.577 (1.366–1.821) #

1.491 (1.266–1.756) #

FT3FT4

1

457/2945 (15.5)

1

1

1

1

2

528/2958 (17.8)

1.183 (1.031–1.357)

1.241 (1.080–1.426)

1.220 (1.060–1.405) #

1.234 (1.054–1.445)

3

667/2960 (22.5)

1.584 (1.388–1.807) #

1.753 (1.533–2.005) #

1.731 (1.512–1.983) #

1.537 (1.318–1.791) #

4

789/2956 (26.7)

1.982 (1.743–2.255) #

2.263 (1.984–2.582) #

2.267 (1.984–2.590) #

1.674 (1.438–1.948) #

  1. Model 1: crude; model 2: adjusted for age; model 3: adjusted for age, current smoking and alcohol consumption
  2. model 4: adjusted for age, BMI, current smoking and alcohol consumption
  3. OR and 95% CI for metabolic syndrome were calculated using logistic regression models
  4. Significant associations (P < 0.001) are shown in bold