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Table 1 Basic information about the IGR, NGT and T2DM groups

From: Association of insulin, C-peptide and blood lipid patterns in patients with impaired glucose regulation

 

NGT (n = 68)

IGR (n = 112)

T2DM (n = 174)

P-value NGT vs IGR

P-value NGT vs T2DM

P-value IGR vs T2DM

Male

42

66

92

   

Female

26

46

82

   

Age (years)

53 ± 10

53 ± 9

55 ± 10

1.000

0.163

0.087

BMI (kg/m2)

23.88 ± 2.59

25.91 ± 3.21

24.52 ± 3.08

<  0.001

0.131

0.001

Waist circumference (cm)

82.09 ± 8.47

92.60 ± 10.53

90.43 ± 7.68

<  0.001

<  0.001

0.045

WHR

0.83 ± 0.07

0.93 ± 0.06

0.91 ± 0.05

<  0.001

<  0.001

0.003

SBP (mmHg)

128.54 ± 15.71

132.94 ± 12.99

135.96 ± 16.37

0.044

0.002

0.101

DBP (mmHg)

76.46 ± 11.55

81.47 ± 8.77

81.43 ± 9.36

0.001

0.001

0.971

TG (mmol/L)

1.38 ± 0.71

1.95 ± 1.02

1.78 ± 0.74

<  0.001

0.001

0.104

TC (mmol/L)

4.99 ± 0.99

5.82 ± 0.86

5.48 ± 1.10

<  0.001

0.002

0.006

HDL-C (mmol/L)

1.35 ± 0.39

1.27 ± 0.24

1.30 ± 0.26

0.090

0.248

0.327

LDL-C (mmol/L)

2.16 ± 0.75

3.21 ± 0.83

3.02 ± 0.82

<  0.001

<  0.001

0.058

FBG (mmol/L)

5.04 ± 0.57

6.08 ± 0.70

8.37 ± 1.56

<  0.001

<  0.001

< 0.001

HbA1c (%)

5.52 ± 0.44

6.33 ± 0.40

9.76 ± 2.79

<  0.001

<  0.001

< 0.001

FINS (mU/mL)

10.50 ± 4.85

11.61 ± 5.90

8.14 ± 5.22

0.193

0.001

< 0.001

C-peptide (μg/L)

3.10 ± 0.86

3.23 ± 1.49

2.12 ± 0.67

0.513

<  0.001

< 0.001

HOMA-IR*

2.42 ± 0.48

2.85 ± 0.53

3.00 ± 0.67

<  0.001

<  0.001

0.046

HOMA-β*

4.78 ± 0.46

4.05 ± 0.33

3.72 ± 0.52

<  0.001

<  0.001

< 0.001

QUICKI *

0.375 ± 0.02

0.356 ± 0.01

0.336 ± 0.01

<  0.001

<  0.001

<  0.001

Matsuda index

14.92 ± 2.86

8.07 ± 1.47

5.87 ± 1.31

<  0.001

<  0.001

< 0.001

  1. *Adjusted for BMI; BMI Body Mass Index, WHR Waist-to-Hip Ratio, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, TG Triglyceride, TC Total Cholesterol, HDL-C High Density Lipoprotein Cholesterol, LDL-C Low Density Lipoprotein-Cholesterol, FBG Fasting Blood Glucose, HbA1c Hemoglobin A1c, FINS Fasting Insulin, HOMA-IR Homeostasis Model Assessment-Insulin Resistance index, HOMA-β Homeostasis Model Assessment -pancreatic β cell function index, QUICKI Quantitative Insulin Sensitivity Check Index
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BMC Endocrine Disorders

ISSN: 1472-6823

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