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Fig. 1 | BMC Endocrine Disorders

Fig. 1

From: Medullary thyroid carcinoma with double negative calcitonin and CEA: a case report and update of literature review

Fig. 1

Thyroid definitive pathology with microscopic and immunochemistry evaluation a) Low magnification showed nests of neoplastic cells separated by thick septa of fibrous tissue (haematoxylin and eosin, original magnification, x4); b) The neoplastic cells have a plasmacytoid appearance (haematoxylin and eosin, original magnification, x20); c-f) Phenotypic features with positivity for cytokeratin 19 (c: immunoperoxidase stain for anti-cytokeratin 19, original magnification, x 20), calcitonin (d: immunoperoxidase stain for anti-calcitonin, original magnification, x 20), weak expression of CD56 (e: immunoperoxidase stain for anti-CD56, original magnification, x 20) and negativity for thyroglobulin (f: immunoperoxidase stain for anti-thyroglobulin, original magnification, x 20)

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BMC Endocrine Disorders

ISSN: 1472-6823

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