Table 1 clinical and biological parameters during intensive care unit stay
From: Extremely high-dose insulin requirement in a diabetic patient with COVID-19: a case report
Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 | Day 8 | Day 9 | Day 10 | Day 11 | Day 12 | Day 13 | Day 14 | Day 15 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total insulin requirement per day (UI) | 10 iv | 120 iv | 384 iv | 633 iv | 1035 iv | 583 iv | 387 iv | 554 iv | 348 iv | 78 iv | 84 iv | 85 iv | 65 iv | 60 sc | 60 sc |
CRP (mg/l) | 179 | 275 | 300 | 251 | 192 | 199 | 169 | 98 | 43 | 72 | 101 | 95 | 79 | – | 22 |
PCT (μg/l) | 0.56 | 0.86 | 0.74 | 0.7 | – | 0.93 | – | 0.57 | 0.49 | 0.77 | – | – | – | 0.31 | – |
Nutrition | Enteral | Enteral | Enteral | Enteral | Enteral | Enteral | Enteral | Enteral | Enteral | Enteral | Enteral | Enteral | Enteral | Enteral | Enteral |
Carbohydrates (g) | 91.5 | 91.5 | 141.55 | 141.5 | 141.5 | 141.5 | 141.5 | 141.5 | 141.5 | 183 | 183 | 183 | 183 | 183 | 183 |
Corticosteroids | – | – | – | – | – | Hydrocortisone 50 mg 3x/d | Hydrocortisone 50 mg 3x/d | Hydrocortisone 50 mg 3x/d | – | – | – | – | – | – | – |
vasopressor infusion (norepinephrine) (μg/kg/min) | 0.22 | 0.28 | 0.28 | 0.21 | 0.20 | 0.16 | 0.04 | 0.02 | No | No | No | No | No | No | No |
Plasma glucose level (mg/dl) | 106 | 227 | 232 | 290 | 274 | 260 | 243 | 234 | 155 | 137 | 216 | 229 | 155 | 157 | 122 |
Clinical evolution | Admission at Intensive care unit and oro-tracheal intubation | Extubation | Transfer to the intermediate care unit |