Variables | Tertile 1 | Tertile 2 | Tertile 3 | P-value |
---|---|---|---|---|
(< 0.41) | (0.41–0.56) | (> 0.56) | ||
N = 107 | N = 96 | N = 99 | ||
Baseline characteristics | ||||
Age, years | 57.19 ± 9.27 | 55.81 ± 12.01 | 59.53 ± 10.17 | 0.045 |
Male, n (%) | 65(60.7) | 67(69.8) | 64(64.6) | 0.402 |
BMI, kg/m2 | 26.09 ± 3.03 | 27.00 ± 3.42 | 26.20 ± 2.95 | 0.092 |
Family history of CAD, n (%) | 14(13.1) | 18(18.8) | 10(10.1) | 0.173 |
HTN, n (%) | 76(71.0) | 66(68.8) | 75(75.8) | 0.538 |
CAD, n (%) | 71(66.4) | 72(75.0) | 89(89.9) | < 0.001 |
Stroke, n (%) | 6(5.6) | 5(5.2) | 6(6.1) | 0.972 |
Smoking, n (%) | 53(49.5) | 54(56.3) | 47(47.5) | 0.516 |
Alcohol drinker, n (%) | 36(33.6) | 33(34.4) | 33(33.3) | 0.993 |
Carotid plaque, n (%) | 43(40.2) | 53(55.2) | 69(69.7) | < 0.001 |
Laboratory parameters | ||||
FPG, mmol/L | 6.89 ± 1.96 | 7.57 ± 2.01 | 7.84 ± 2.40 | 0.005 |
HbA1c (%) | 7.15 ± 1.21 | 7.21 ± 1.34 | 7.63 ± 1.36 | 0.022 |
TC, mmol/L | 4.20 ± 1.19 | 4.13 ± 1.31 | 4.54 ± 1.35 | 0.060 |
LDL-C, mmol/L | 2.55 ± 0.97 | 2.56 ± 1.13 | 2.72 ± 1.20 | 0.469 |
HDL-C, mmol/L | 1.00 ± 0.28 | 0.99 ± 0.27 | 1.07 ± 0.29 | 0.097 |
TG, mmol/L | 1.46(1.27–2.21) | 1.63(1.25–2.36) | 1.82(1.20–2.88) | 0.127 |
ApoA, g/L | 1.29 ± 0.24 | 1.35 ± 0.67 | 1.38 ± 0.25 | 0.295 |
ApoB, g/L | 0.90 ± 0.30 | 0.88 ± 0.30 | 0.91 ± 0.29 | 0.697 |
Lp(a), mg/dL | 116.75(51.55–354.49) | 156.4(60.33–316.70) | 95.3(52.70–214.20) | 0.121 |
Hs-CRP, mg/dL | 1.28(0.63–2.82) | 1.47(0.84–2.98) | 1.58(0.82–2.50) | 0.509 |
FFAs, mmol/L | 0.32 ± 0.07 | 0.49 ± 0.04 | 0.68 ± 0.11 | <0.001 |
Gensini score | 19.0(8.0–41.5) | 30.0(8.0–64.0) | 46.0(16.0–86.0) | <0.001 |
Crouse score | 2.40 ± 1.47 | 3.02 ± 1.55 | 3.34 ± 1.73 | <0.001 |
Medicines | ||||
Aspirin, n (%) | 56(52.3) | 56(58.3) | 65(65.7) | 0.496 |
Statin, n (%) | 48(44.9) | 48(50.0) | 49(49.5) | 0.717 |
ACEI, n (%) | 11(10.3) | 15(15.6) | 8(8.1) | 0.278 |
ARB, n (%) | 17(15.9) | 15(15.6) | 12(12.1) | 0.519 |
Calcium Blocker, n (%) | 21(19.6) | 19(19.8) | 20(20.2) | 0.956 |