| T2D with CRC | T2D without CRC | p |
---|---|---|---|
Number of patients | 50 | 100 | – |
Sex (male %) | 66 | 54 | 0.160 |
Age (yr) | 69.44 ± 7.73 | 67.29 ± 7.83 | 0.114 |
Duration of diabetes (yr) | 11.50 (5.00–15.00) | 10.00 (6.00–18.00) | 0.743 |
BMI (kg/m2) | 24.70 ± 2.04 | 25.25 ± 3.21 | 0.205 |
TG (mmol/L) | 1.98 (1.64–2.33) | 1.65 (1.08–2.30) | 0.028 |
TC (mmol/L) | 4.78 (4.33–5.04) | 4.33 (3.43–4.98) | 0.013 |
LDL-c (mmol/L) | 2.64 ± 0.58 | 2.42 ± 0.83 | 0.061 |
HDL-c (mmol/L) | 1.16 ± 0.40 | 1.16 ± 0.27 | 0.957 |
HOMA-IR | 3.93 (2.43–5.46) | 3.66 (1.75–5.61) | 0.539 |
Fasting plasma glucose (mmol/L) | 7.41 (5.92–9.47) | 7.73 (6.27–9.37) | 0.534 |
Fasting C-peptide (nmol/L) | 0.83 (0.66–1.06) | 0.74 (0.51–1.05) | 0.096 |
Fasting serum insulin (pmol/L) | 83.48 (63.47–109.38) | 72.43 (43.22–100.78) | 0.191 |
Hemoglobin A1c (%) | 8.09 ± 0.79 | 8.47 ± 1.77 | 0.071 |
IL-6 (ng/L) | 78.70 (58.23–114.17) | 24.49 (14.00–36.05) | <0.001 |
sRAGE (ng/L) | 604.61 ± 210.21 | 404.80 ± 166.18 | <0.001 |
Current smoker (%) | 26 | 15 | 0.103 |
Insulin use (%) | 34 | 84 | <0.001 |
Sulfonylurea use (%) | 32 | 45 | 0.127 |
Metformin use (%) | 16 | 83 | <0.001 |
Thiazolidinedione use (%) | 0 | 13 | 0.018 |
a-Glucosidase inhibitor use (%) | 12 | 62 | <0.001 |
NSAID use (%) | 8 | 41 | <0.001 |
Statin use (%) | 6 | 40 | <0.001 |