Skip to main content

Table 1 General characteristics of HP and PHP subjects

From: Manifestations of left ventricular dysfunction and arrhythmia in patients with chronic hypoparathyroidism and pseudohypoparathyroidism: a preliminary study

Characteristic

HP N = 18

PHP N = 8

P

Female, n (%)

12 (66.7%)

7 (87.5%)

0.375

Age of onset (y)

23.9 ± 13.8

12.9 ± 7.4

0.045

Course (y)

22.5 ± 15.8

9.2 ± 11.9

0.046

Age of heart evaluation (y)

45.4 ± 15.4

22.1 ± 6.4

0.000

BMI (kg/m2)

25.1 ± 3.9

22.2 ± 2.6

0.074

Diabetes, n

1

0

0.692

CAD, n

0

0

NA

Hypertension, n

4

0

0.205

Systolic BP (mmHg)

119.4 ± 12.0

107.6 ± 13.8

0.040

Diastolic BP (mmHg)

74.4 ± 9.0

72.9 ± 11.1

0.714

Serum calcium (mmol/L)

2.05 ± 0.16

2.25 ± 0.19

0.011

Serum phosphorus (×ULN)

1.13 ± 0.10

0.99 ± 0.12

0.003

Serum magnesium (mmol/L)

0.82 ± 0.07

0.85 ± 0.08

0.464

Serum potassium (mmol/L)

4.07 ± 0.26

4.10 ± 0.31

0.770

25(OH)2D (ng/mL)

23.8 [17.7, 41.4]

32.0 [19.9, 83.4]

0.500

Fasting blood glucose (mmol/L)

5.3 ± 0.4

4.9 ± 0.4

0.020

PTH (pg/mL)

3 [2.6, 7.9]

237.4 [43.9482.9]

0.000

ALP (×ULN)

0.54 ± 0.17

0.71 ± 0.37

0.111

β-CTX (×ULN)

0.74 ± 0.32

1.37 ± 0.69

0.008

eGFR (MDRD) (mL/min/1.73m2)

90.4 ± 21.1

127.3 ± 29.7

0.005

Total cholesterol (mmol/L)

4.6 ± 0.7

3.7 ± 2.0

0.178

Triglycerides (mmol/L)

1.3 ± 0.9

0.7 ± 0.6

0.181

LDL-C (mmol/L)

2.7 ± 0.4

2.2 ± 1.3

0.361

HDL-C (mmol/L)

1.1 ± 0.2

1.0 ± 0.5

0.619

CK (U/L)

126.5 [63.8, 145.8]

85.0 [67.5, 118.3]

0.153

CKMB (μg/L)

0.40 [0, 0.80]

0.45 [0.03, 0.65]

0.776

cTnI (μg/L)

<  0.017

<  0.017

BNP (ng/L)

13.0 [8.0, 25.8]

6.5 [3.3, 11.8]

0.070

  1. Date represent the means (SD), median (P25, P75), or N (%)
  2. Abbreviations: HP hypoparathyroidism; PHP pseudohypoparathyroidism; BMI body mass index; CAD coronary artery disease; BP blood pressure; PTH parathyroid hormone; ALP alkaline phosphatase; β-CTX C-terminal telopeptide of type I collagen; eGFR estimated glomerular filtration rate; LDL-C low-density lipoprotein cholesterol; HDL-C high-density lipoprotein cholesterol; CK creatine kinase; CKMB creatine kinase-myocardial isoenzyme; cTnI cardiac troponin I; BNP B-type natriuretic peptide