Table 2 Allele frequencies and genotype distribution of CD160 polymorphisms in AITD patients and controls
From: Associations between CD160 polymorphisms and autoimmune thyroid disease: a case-control study
Gene/SNP | Controls | AITD | P value | GD | P-Value | HT | P value |
|---|---|---|---|---|---|---|---|
CD160 | n (%) | n (%) | AITD vs. Control | n (%) | GD vs. Control | n (%) | HT vs. Control |
rs744877 | |||||||
A | 1130 (66%) | 1399 (68.78%) | 0.071 | 885 (69.69%) | 0.034 | 514 (67.10%) | 0.593 |
C | 582 (34%) | 635 (31.22%) | 385 (30.31%) | 252 (32.90%) | |||
AA | 361 (42.17%) | 487 (47.89%) | 0.031 | 314 (49.53%) | 0.014 | 173 (45.17%) | 0.464 |
AC | 408 (47.66%) | 425 (41.79%) | 257 (40.54%) | 168 (43.86%) | |||
CC | 87 (10.17%) | 105 (10.32%) | 63 (9.93%) | 42 (10.97%) | |||
rs3766526 | |||||||
G | 1406 (82.13%) | 1636 (80.43%) | 0.186 | 1013 (79.89%) | 0.123 | 623 (81.33%) | 0.635 |
A | 306 (17.87%) | 398 (19.57%) | 255 (20.11%) | 143 (18.67%) | |||
GG | 574 (67.06%) | 659 (64.80%) | 0.319 | 407 (64.20%) | 0.187 | 252 (65.80%) | 0.888 |
GA | 258 (30.14%) | 318 (31.27%) | 199 (31.39%) | 119 (31.07%) | |||
AA | 24 (2.80%) | 40 (3.93%) | 28 (4.41%) | 12 (3.13%) | |||