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Table 1 Characteristics of bone status in postmenopausal women

From: Klotho reduces the risk of osteoporosis in postmenopausal women: a cross-sectional study of the National Health and Nutrition Examination Survey (NHANES)

Variables

Non-OP (n = 796)

OP (n = 89)

P-value

Age (year)

61.9 ± 7.5

65.7 ± 7.5

< 0.001 **

Race

  

< 0.001 **

 Mexican American

135(17.3)

11(12.36)

 

 Non-Hispanic black

155(19.8)

7(7.87)

 

 Non-Hispanic white

351(44.9)

42(47.19)

 

 Other Hispanic

92(11.8)

13(14.61)

 

 Other racea

49(6.3)

16(17.98)

 

 Dietary energy (kcal)

1651.8 ± 573.7

1679.5 ± 703.6

0.721

 Dietary protein (gm)

65.4 ± 24.2

64.2 ± 26.2

0.677

 Dietary sodium (mg)

2725.2 ± 1049.9

2647.4 ± 1044.9

0.507

 Dietary potassium (mg)

2366.5 ± 880.7

2289.3 ± 951.1

0.467

 Dietary calcium (mg)

814.5 ± 401.0

830.1 ± 494.2

0.774

 Dietary phosphorus (mg)

1117.5 ± 401.1

1102.3 ± 482.7

0.776

 BMI (kg/m2)

30.1 ± 6.5

25.4 ± 5.2

< 0.001 **

BMIb

  

< 0.001 **

 Non obesity

170(21.7)

46(51.69)

 

 Overweight

364(46.5)

12(13.48)

 

 Obesity

248(31.7)

31(34.83)

 

 Serum total calcium (mmol/l)

2.4 ± 0.1

2.4 ± 0.1

0.490

 Serum total phosphorus (mmol/l)

1.26 ± 0.17

1.30 ± 0.18

0.087 *

 Log2.Klotho (pg/ml)c

9.70[9.40,10.00]

9.57[9.27,9.80]

0.003 **

 Pregnancy timesd

2.8 ± 1.9

3.2 ± 2.0

0.091 *

CKD

  

0.052 *

 No

700(89.5)

73(82.02)

 

 Yes

82(10.5)

16(17.98)

 

Smoking history

  

0.380

 Never

421(53.8)

50(56.18)

 

 Former smoker

234(29.9)

21(23.60)

 

 Smoker

127(16.2)

18(20.22)

 

Drinking history

  

0.584

 Never

145(18.5)

21(23.60)

 

 Former drinker

170(21.7)

20(22.47)

 

 Mild drinker

257(32.9)

25(28.09)

 

 Moderate drinker

134(17.1)

12(13.48)

 

 Heavy drinker

76(9.7)

11(12.36)

 

Hypertension

  

0.844

 No

303(38.7)

36(40.45)

 

 Yes

479(61.3)

53(59.55)

 

Diabetese

  

0.830

 No

481(61.5)

57(64.04)

 

 IGT

93(11.9)

11(12.36)

 

 Yes

208(26.6)

21(23.60)

 

CVD

  

0.543

 No

690(88.2)

76(85.39)

 

 Yes

92(11.8)

13(14.61)

 

COPD

  

0.458

 No

725(92.7)

80(89.89)

 

 Yes

57(7.3)

9(10.11)

 
  1. BMI Body mass index, CKD Chronic kidney disease, CVD Chronic vascular disease, COPD Chronic obstructive pulmonary disease
  2. a.Other race including others not mentioned above, including multi-racial
  3. b.Classify BMI according to CDC standard
  4. c.Logarithm of plasma Klotho
  5. d.Refers to the number of pregnancies over 28 weeks, including live births and stillbirths
  6. e.Classification according to ADA-2013 guidelines
  7. *P < 0.1
  8. **P < 0.05