Fig. 6
From: High expression of IL4I1 is correlated with poor prognosis and immune infiltration in thyroid cancer
The effects of IL4I1 on cell proliferation and metastasis in vitro. A 8505C cell (ATC) had the highest IL4I1 expression in the thyroid cancer cell lines K1, KTC-1, TPC-1 and 8505C tested by qPCR (** p < 0.01). B 8505C cell with IL4I1 knocked down by lentivirus containing shRNA targeting IL4I1 (8505C-shIL4I1) had lower IL4I1 expression compared with its control (8505C-vector) (** p < 0.01). C 8505C-shIL4I1 cell had lower IL4I1 protein level compared with 8505C-vector (cropping blots). D The cell proliferation assay showed the impaired proliferation without IL4I1 (*** p < 0.001). E The migration and invasion ability of 8505C-shIL4I1 cell was significantly weaken (** p < 0.01)