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Table 4 Biochemical parameters of study participants across different tertiels of dietary choline, betaine and total choline and betaine intake

From: The interactive relationship of dietary choline and betaine with physical activity on circulating creatine kinase (CK), metabolic and glycemic markers, and anthropometric characteristics in physically active young individuals

Variables

Total choline

Total betaine

Total choline and betaine

T1 (n = 40)

T2 (n = 40)

T3 (n = 40)

*P

**P

T1 (n = 40)

T2 (n = 40)

T3 (n = 40)

*P

**P

T1 (n = 40)

T2 (n = 40)

T3 (n = 40)

*P

**P

FBS (mg/dl)

70.83 (8.33)

70.97 (7.80)

69.70 (6.86)

0.832

0.538

70.59 (8.00)

70.65 (7.94)

70.26 (7.15)

0.969

0.499

70.08 (8.20)

72.16 (7.23)

69.25 (7.36)

0.209

0.075

Insulin (µ IU/ml)

10.45 (10.09)

8.94 (5.01)

9.41 (5.97)

0.881

0.572

11.54 (10.37)

8.86 (4.17)

8.43 (5.08)

0.116

0.175

10.47 (10.13)

9.33 (5.94)

9.00 (4.97)

0.641

0.620

TC (mg/dl)

208.06 (61.71)

205.19 (56.79)

185.95 (53.51)

0.172

0.671

209.40 (44.93)

218.17 (65.20)

171.67 (51.25)

< 0.001

0.032b

206.44 (52.65)

208.44 (63.26)

184.29 (54.97)

0.110

0.150

HDL (mg/dl)

47.76 (11.36)

50.73 (11.88)

48.40 (11.07)

0.469

0.524

45.43 (9.34)

52.16 (11.89)

49.25 (12.05)

0.028

0.049a

46.48 (11.39)

50.93 (10.91)

49.45 (11.78)

0.205

0.545

LDL (mg/dl)

135.21 (67.72)

127.34 (59.52)

113.67 (53.70)

0.272

0.784

141.30 (46.56)

138.84 (70.47)

96.23 (52.44)

0.001

0.183

136.82 (60.70)

130.66 (61.88)

10,878 (57.24)

0.090

0.428

TG (mg/dl)

125.44 (80.83)

135.54 (64.16)

119.39 (63.97)

0.399

0.272

113.35 (66.02)

135.79 (75.95)

130.94 (66.45)

0.317

0.312

115.65 (81.38)

134.19 (57.36)

130.29 (69.11)

0.456

0.325

CK (U/L)

209.51 (67.49)

201.80 (76.43)

345.40 (543.41)

0.174

0.092

198.03 (77.09)

270.60 (333.84)

287.80 (443.93)

0.423

0.582

200.28 (69.20)

219.00 (78.44)

337.20 (544.84)

0.118

0.142

HOMA-IR

1.86 (1.89)

1.57 (0.91)

1.64 (1.07)

0.912

0.573

2.05 (2.00)

1.56 (0.80)

1.46 (0.87)

0.111

0.143

1.85 (1.90)

1.63 (1.07)

1.55 (0.88)

0.591

0.544

QUICKI

0.36 (0.03)

0.36 (0.03)

0.37 (0.04)

0.912

0.624

0.36 (0.03)

0.36 (0.03)

0.37 (0.04)

0.179

0.226

0.36 (0.03)

0.36 (0.03)

0.37 (0.04)

0.623

0.425

  1. FBS Fasting blood sugar, TC Total cholesterol, HDL High-density lipoprotein, LDL Low-density lipoprotein, TG Triglycerides, CK Creatine kinase. *P Significant at P < 0.05; 95th confidence intervals of the difference in parentheses. **P values are obtained from ANCOVA model after adjustment for the confounding effects of age, sex, BMI and physical activity, calorie intake and further adjusted for muscle mass for CK level
  2. apost hoc Tukey signature difference between 1st tertile and 2nd tertile
  3. bpost hoc Tukey signature difference between 2nd tertile and 3rd tertile