Table 1 Demographics N = 93. FC: Full Cohort. SC: Stable Cohort where TSH is within normal range

Female, N (%)

86 (92.5%)

72(94.7%)

Male, N (%)

7 (7.5%)

4 (5.3%)

Age, Mean(range)

44.7 (19–83)

46.45 (21–83)

Weight, Mean(range)

75.6 (46.3-129.1)

*missing = 2

75.5 (46.3-129.1)

*missing = 1

Height, Mean(range)

162.1 (149–187)

*missing = 1

162.1 (149–187)

Waist circumference, Mean(range)

97.34 (74–159)

*missing = 1

97.9 (74–159) *

*Missing = 16

BMI, Mean(range)

28.8 (18.3–45.7)

*missing = 2

28.8 (18.4–45.7)

*Missing = 1

Nationality, N (%)

Jordanian 90 (96.8%)

Iraqi 2 (2.2%)

Syrian 1 (1.1%)

Jordanian 75 (98.7%)

Iraqi 1 (1.3%)

Disease Duration (years)

8 (0.3–32)

*Missing = 5

8.5 (0.3–32)

*Missing = 5

Living area, N (%)

Amman 82(88.2%)

Madaba 3(3.2%)

AlKarak 2(2.2%)

Ajloun 2(2.2%)

AlMafraq 1(1.1%)

AlFuhais 1(1.1%)

AlZarqa 1(1.1%)

AlSalt 1(1.1%)

Amman 67(88.2%)

Madaba 3(3.9%)

AlKarak1(1.3%)

Ajloun 1(1.3%)

AlMafraq 1(1.3%)

AlFuhais 1(1.3%)

AlZarqa 1(1.3%)

AlSalt (1.3%)

Weekly dose T4 (µg), Mean(range)

612.903(75-2500)

599.3 (175–2500)

Daily dose T4 (µg), Mean(range)

87.56 (10.71-357.14)

85.6 (25–357)

Weekly dose (µg) per kg body weight, Mean(range)

8.1 (1.27–28.54)

*missing = 2

8.14 (1.54–28.54)

*Missing = 1

Daily dose (µg) per kg body weight, Mean(range)

1.15 (0.18–4.08)

*missing = 2

1.16 (0.22–4.08)

*Missing = 1

TSH mean (range)

2.38 (0.02–37.32)

1.73 (0.29–4.24)

**Within Lab normal

Free T4 serum level pmol/l

19.4 (8.29–34.49)

19.06 (10.2-27.03)

Free T3 serum level pmol/l

4.51 (2.61–6.39)

1.74 (3.19–6.14)

Antithyroid peroxidase antibodies (AntiTPO)

132.5 (< 9->600)

118.8 (9-600)

AntiTPO (*34 cut off of positivity)

< 34: 46 (49.5%)

< 34: 30 (50%)

> 34: 47(50.5%)

> 34: 30 (50%)

Serum Calcium mmol/L

2.34 (2.08–2.85)

2.4 (2.08–2.85)

Serum Vitamin D nmol/L

70.73 (14.53–190.00)

73.25 (17.5–190)

Serum B12 pmol/L

343.18 (71-2000)

353.9 (71-2000)

B12 supplementation

Yes: 11 (11.8%)

No: 82 (88.2%)

Yes: 9(11.8%)

No: 67(88.2%)

Vitamin D supplementation

Yes: 45 (48.4%)

No: 48 (51.6%)

Yes: 36(47.4%)

No: 40(52.6%)

Calcium supplementation

Yes: 7 (7.5%)

No: 86 (92.5%)

Yes: 6(7.9%)

No: 70(92.1%)

Other supplements

Yes: 29 (31.2%)

No: 64 (68.8%)

Yes: 23(30.3%)

No: 52(68.4%)

Family history of Thyroid disease

No: 31 (33.3%)

Yes: 62 (66.7%)

No: 24(31.6%)

Yes: 52(68.4%)

Adherence

Full adherence: 90 (96.8%)

1 miss per month: 1 (1.1%)

2 miss per month: 1 (1.1%)

3 miss per month: 1 (1.1%)

Full adherence:74 (97.4%)

1 miss per month: 1(1.3%)

3 misses per month: 1(1.3%)

Smoking status

Nonsmoker: 69(74.2%)

Nonsmoker: 57 (75.0%)

Smoker: 20(21.5%)

Smoker: 16(21.1%)

Quit all types: 4(4.3%)

Quit all types: 3(3.9%)