Polymorphism | Genotype | N | Conc T4/dose (mean) | P value, q value | Weekly dose | P value, q value | Daily dose | P value, q value | Weekly dose/kg | P value, q value | Daily dose/kg | P value, q value | TSH | P value, q value | T4 pmol/l | P value, q value | T3 pmol/l | P value, q value | BMI | P value, q value |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
rs11249460 | AA | 9 | 2.04 | 0.766 0.891 | 712.5 | 0.363 0.253 | 101.79 | 0.363 0.253 | 8.62 | 0.556 0.412 | 1.23 | 0.556 0.412 | 2.44 | 0.045# 0.757 | 19.62 | 0.642 0.757 | 4.28 | 0.585 0.834 | 33.87 | 0.02# 0.795 |
 | AG | 39 | 1.65 | 614.1 | 87.73 | 8.50 | 1.21 | 1.73 | 18.74 | 4.34 | 28.09 | |||||||||
 | GG | 27 | 1.58 | 542.4 | 77.49 | 7.45 | 1.06 | 1.52 | 19.34 | 4.47 | 28.05 | |||||||||
rs2235544 | AA | 14 | 2.03 | 0.408 0.800 | 516.07 | 0.485 0.873 | 73.72 | 0.485 0.873 | 7.11 | 0.191 0.757 | 1.02 | 0.191 0.757 | 1.87 | 0.780 0.938 | 18.91 | 0.972 0.978 | 4.36 | 0.002# 0.108* | 28.64 | 0.012# 0.243 |
 | AC | 30 | 1.51 | 642.50 | 91.79 | 9.20 | 1.31 | 1.65 | 19.16 | 4.15 | 26.47 | |||||||||
 | CC | 32 | 1.66 | 595.31 | 85.04 | 7.63 | 1.09 | 1.76 | 19.05 | 4.64 | 30.92 | |||||||||
rs225014 | CC | 10 | 1.26 | 0.074 0.500 | 652.50 | 0.536 0.891 | 93.21 | 0.536 0.891 | 9.02 | 0.406 0.800 | 1.29 | 0.406 0.800 | 1.58 | 0.678 0.938 | 19.25 | 0.938 0.970 | 4.25 | 0.713 0.938 | 30.10 | 0.725 0.938 |
 | CT | 32 | 1.99 | 551.17 | 78.74 | 7.40 | 1.06 | 1.85 | 19.16 | 4.39 | 28.35 | |||||||||
 | TT | 34 | 1.51 | 629.04 | 89.86 | 8.55 | 1.22 | 1.68 | 18.92 | 4.42 | 28.76 | |||||||||
rs225015 | AA | 8 | 1.30 | 0.415 0.800 | 618.75 | 0.799 0.938 | 88.39 | 0.799 0.938 | 8.91 | 0.594 0.891 | 1.27 | 0.594 0.891 | 1.85 | 0.946 0.970 | 19.26 | 0.978 0.978 | 4.30 | 0.863 0.970 | 29.51 | 0.925 0.970 |
 | AG | 32 | 1.87 | 569.92 | 81.42 | 7.58 | 1.08 | 1.73 | 19.00 | 4.37 | 28.80 | |||||||||
 | GG | 36 | 1.59 | 621.18 | 88.74 | 8.45 | 1.21 | 1.72 | 19.08 | 4.41 | 28.59 | |||||||||
rs3806596 | CC | 32 | 1.65 | 0.407 0.800 | 624.22 | 0.295 0.771 | 89.17 | 0.295 0.771 | 8.24 | 0.270 0.757 | 1.18 | 0.270 0.757 | 1.69 | 0.186 0.757 | 19.65 | 0.018# 0.253 | 4.24 | 0.086 0.536 | 29.96 | 0.271 0.757 |
 | CT | 34 | 1.83 | 542.65 | 77.52 | 7.51 | 1.07 | 1.63 | 19.27 | 4.54 | 28.20 | |||||||||
 | TT | 10 | 1.25 | 712.50 | 101.79 | 9.90 | 1.41 | 2.26 | 16.49 | 4.29 | 26.85 | |||||||||
rs3064744 | *1/*28 | 43 | 1.81 | 0.261 0.757 | 602.03 | 0.935 0.970 | 86.00 | 0.935 0.970 | 7.76 | 0.360 0.795 | 1.11 | 0.360 0.795 | 1.69 | 0.652 0.938 | 20.00 | 0.003# 0.108* | 4.31 | 0.218 0.757 | 30.42 | 0.004# 0.108* |
 | *1/*36 | 33 | 1.49 | 595.83 | 85.12 | 8.64 | 1.23 | 1.79 | 17.85 | 4.47 | 26.56 | |||||||||
rs11185644 | CC | 7 | 1.79 | 0.557 0.891 | 521.43 | 0.025# 0.253 | 74.49 | 0.025# 0.253 | 7.62 | 0.056# 0.412 | 1.09 | 0.056# 0.412 | 1.43 | 0.166 0.757 | 20.35 | 0.237 0.757 | 4.60 | 0.443 0.834 | 26.71 | 0.335 0.795 |
 | CT | 28 | 1.48 | 729.91 | 104.27 | 9.59 | 1.37 | 2.01 | 19.52 | 4.31 | 29.95 | |||||||||
 | TT | 41 | 1.79 | 523.48 | 74.78 | 7.21 | 1.03 | 1.60 | 18.53 | 4.40 | 28.31 | |||||||||
rs4588 | GG | 40 | 1.75 | 0.861 0.970 | 540.00 | 0.208 0.757 | 77.14 | 0.208 0.757 | 7.27 | 0.131 0.707 | 1.04 | 0.131 0.707 | 1.83 | 0.703 0.938 | 19.04 | 0.878 0.970 | 4.42 | 0.697 0.938 | 29.04 | 0.839 0.970 |
 | GT | 33 | 1.60 | 674.24 | 96.32 | 9.21 | 1.32 | 1.63 | 19.17 | 4.36 | 28.35 | |||||||||
 | TT | 3 | 1.57 | 566.67 | 80.95 | 7.58 | 1.08 | 1.65 | 18.19 | 4.16 | 29.91 | |||||||||
rs602662 | AA | 27 | 1.75 | 0.578 0.891 | 537.04 | 0.267 0.757 | 76.72 | 0.267 0.757 | 7.66 | 0.342 0.795 | 1.09 | 0.342 0.795 | 1.74 | 0.711 0.938 | 18.85 | 0.897 0.970 | 4.32 | 0.778 0.938 | 28.06 | 0.749 0.938 |
 | AG | 40 | 1.72 | 610.62 | 87.23 | 8.04 | 1.15 | 1.68 | 19.15 | 4.41 | 29.19 | |||||||||
 | GG | 9 | 1.28 | 736.11 | 105.16 | 9.96 | 1.42 | 1.98 | 19.35 | 4.45 | 29.00 |