Table 2 Clinical characteristics of participants according to quartiles of FGF-21

Male, %

52 (59.09)

45 (51.72)

42 (48.28)

44 (50.00)

0.496

0.197

Age, years

53.35 ± 11.58

51.69 ± 11.17

55.52 ± 11.08

54.19 ± 11.17

0.242

0.153

Height, cm

161.61 ± 7.09

160.68 ± 9.41

160.19 ± 9.54

159.68 ± 10.70

0.557

0.155

Weight, kg

61.62 ± 11.25

63.40 ± 13.83

63.24 ± 10.32

66.03 ± 12.99

0.118

0.025

BMI, kg/m²

23.48 ± 3.25

24.39 ± 4.05

24.59 ± 3.17

25.79 ± 3.86^*

< 0.001

< 0.001

Waistline, cm

82.00 ± 9.43

84.18 ± 10.60

84.86 ± 7.59

87.93 ± 10.08^*#

< 0.001

< 0.001

Hipline, cm

94.09 ± 6.36

95.06 ± 7.67

95.91 ± 4.94

98.02 ± 7.90^*#

0.001

< 0.001

WHR

0.87 ± 0.06

0.88 ± 0.07

0.88 ± 0.05

0.90 ± 0.06^*

0.052

0.009

SBP, mmHg

121.93 ± 14.25

121.84 ± 14.18

122.75 ± 13.87

128.14 ± 18.20^*#

0.017

0.008

DBP, mmHg

74.16 ± 9.14

74.59 ± 8.83

76.06 ± 9.89

77.44 ± 10.73

0.101

0.015

TC, mmol/L

5.31 ± 0.86

5.45 ± 1.00

5.26 ± 0.95

5.67 ± 1.15^@

0.033

0.065

TG, mmol/L

1.04 (0.75, 1.50)

1.28 (0.91, 1.81) ^*

1.43 (1.16, 1.99) ^*

1.76 (1.24, 3.09) ^*#@

< 0.001

< 0.001

HDL-C, mmol/L

1.44 ± 0.31

1.52 ± 0.43

1.51 ± 0.67

1.46 ± 0.64

0.683

0.882

LDL-C, mmol/L

3.27 ± 0.69

3.27 ± 0.84

3.11 ± 0.86

3.36 ± 0.92

0.251

0.792

FPG, mmol/L

5.65 ± 2.13

5.47 ± 1.55

5.84 ± 1.97

6.38 ± 2.38^#

0.020

0.008

HbA1c, %

5.97 ± 1.48

6.02 ± 1.44

6.08 ± 0.94

6.24 ± 1.11

0.511

0.144