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Table 3 Clinical characteristics of participants in different clusters

From: The association of FGF-21 with the risk of newly diagnosed type-2 diabetes mellitus: a cross-sectional study in Southern China

Variables

Cluster 1

Cluster 2

P difference

Male, %

107 (47.13)

76 (61.79)

0.012

Age, years

54.26 ± 11.42

52.64 ± 11.03

0.202

Height, cm

159.89 ± 8.45

161.74 ± 10.53

0.076

Weight, kg

58.24 ± 8.96

73.41 ± 11.32

< 0.001

BMI, kg/m2

22.69 ± 2.34

28.02 ± 3.16

< 0.001

Waistline, cm

79.87 ± 6.73

93.74 ± 7.68

< 0.001

Hipline, cm

92.86 ± 5.32

101.15 ± 6.37

< 0.001

WHR

0.86 ± 0.05

0.93 ± 0.06

< 0.001

SBP, mmHg

120.16 ± 13.10

130.15 ± 17.17

< 0.001

DBP, mmHg

73.05 ± 8.55

80.20 ± 10.08

< 0.001

TC, mmol/L

5.32 ± 0.92

5.61 ± 1.13

0.010

TG, mmol/L

1.15 (0.84, 1.53)

2.05 (1.49, 3.01)

< 0.001

HDL-C, mmol/L

1.53 ± 0.46

1.38 ± 0.63

0.012

LDL-C, mmol/L

3.21 ± 0.75

3.34 ± 0.96

0.166

FPG, mmol/L

5.30 ± 1.37

6.82 ± 3.66

< 0.001

HbA1c, %

5.82 ± 1.05

6.55 ± 1.48

< 0.001

FGF-21, pg/mL

152.6 (98.6, 244.4)

247.7 (146.3, 339.5)

0.005

  1. Cluster 1, termed as the relatively healthy population, was characterized by relatively low BMI, waistline, SBP, TG, and FPG;
  2. Cluster 2, labeled as metabolic derangement subjects, was characterized by higher level of BMI, waistline, SBP, TG, and FPG.