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Table 1 Characteristics of all the study participants categorized by the presence of NAFLD on ultrasound

From: Follicle-stimulating hormone is negatively associated with nonalcoholic fatty liver disease in a Chinese elderly population: a retrospective observational study

 

ALL

Non-NAFLD

NAFLD

P value

N = 455

(n = 255)

(n = 200)

Demography

Age(ys)

71.44 ± 8.80

71.39 ± 8.38

71.51 ± 9.33

0.888

Men(%)

21.5%(98)

24.3%(62)

18%(36)

0.109

Current smoker(%)

9.67% (44)

11% (28)

8% (16)

0.292

systolic BP (mmHg)

136.49 ± 20.17

133.76 ± 19.20

139.75 ± 20.87

0.005

diastolic BP (mmHg)

74.06 ± 10.79

73.79 ± 11.54

74.38 ± 9.85

0.602

Fat-related

Waist (cm)

82.82 ± 7.96

82.82 ± 7.96

87.73 ± 12.64

0.003

BMI

24.06 ± 3.62

22.34 ± 3.04

25.62 ± 3.40

< 0.001

Glucose-related

FBG (mmol/L)

6.92 ± 2.88

6.38 ± 2.47

7.59 ± 3.2

< 0.001

PPG (mmol/L)

9.25 ± 4.46

9.22 ± 5.04

9.27 ± 3.96

0.954

Liver Enzyme-related (IU/L)

ALT†

21.80 ± 13.64

19.79 ± 12.12

24.36 ± 14.20

< 0.001

AST

21.48 ± 10.58

22.20 ± 10.02

22.85 ± 11.27

0.512

Lipid-related

TC (mmol/L)

4.75 ± 1.13

4.74 ± 1.16

4.76 ± 1.08

0.895

HDL-c(mmol/L) †

1.27 ± 0.41

1.36 ± 0.44

1.15 ± 0.33

< 0.001

LDL-c(mmol/L)

3.02 ± 1.01

2.99 ± 1.05

3.08 ± 0.96

0.347

triglycerides (mmol/L) †

1.59 ± 1.19

1.33 ± 1.03

1.93 ± 1.29

< 0.001

SEX hormone

FSH† (IU/L)

54.63 ± 31.35

61.39 ± 33.61

52.68 ± 27.01

0.004

estradiol (pg/ml)

31.19 ± 22.62

30.66 ± 21.45

28.53 ± 20.52

0.285

testosterone† (nmol/L)

3.59 ± 5.41

4.34 ± 6.23

2.76 ± 4.19

0.027

Syndrome-related(%)

Dyslipidemia

66.08%(301)

61. 2% (156)

72.5% (145)

0.001

Hypertension

64.18%(292)

57.6% (147)

72.5% (145)

< 0.001

Obesity

62.64% (285)

48.2% (123)

81.0% (162)

< 0.001

DM related(%)

   

< 0.001

NGT

43.30%(197)

52.9%(135)

31%(62)

 

IGT

6.4%(29)

3.9%(10)

9.5%(19)

 

DM

50.33%(229)

43.1%(110)

59.5%(119)

 

Metabolic syndrome

74.51%(339)

64.7%(165)

87% (174)

< 0.001

  1. Data were expressed as the means ± SD, frequencies
  2. †Logarithmically transformed when compared
  3. NAFLD: nonalcoholic fatty liver disease; BP: blood pressure; BMI: body mass index; FBG: fasting blood glucose; PPG: postload plasma glucose; ALT: alanine aminotransferase; AST: aspartate aminotransferase; TC: total cholesterol; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol; FSH: follicle-stimulating hormone; NGT: normal glucose tolerance; IGT: impaired glucose tolerance; DM: diabetes mellitus