I(11.2–12.4%) | II(12.5–12.9%) | III(13.0–18%) | P | |
---|---|---|---|---|
n | 163 | 164 | 160 | |
male (%) | 93(57.1%)#Δ | 75(45.7%)*Δ | 62(38.8%)*# | < 0.01 |
Age (years) | 57.0 ± 16.9#Δ | 58.4 ± 16.7*Δ | 60.1 ± 17.1*# | < 0.01 |
duration(years) | 6.3 ± 4.5#Δ | 6.9 ± 4.6*Δ | 7.1 ± 4.8*# | < 0.01 |
BMI (kg/m2) | 21.8 ± 4.2 | 22.7 ± 4.6 | 22.6 ± 4.3 | 0.546 |
SBP (mmHg) | 127.9 ± 18.8 | 129.3 ± 18.4 | 128.8 ± 18.9 | 0.509 |
DBP (mmHg) | 71.7 ± 18.2 | 71.3 ± 18.6 | 72.1 ± 17.8 | 0.648 |
TG (mmol/L) | 1.6 ± 0.5#Δ | 1.5 ± 0.6*Δ | 1.4 ± 0.6*# | 0.043 |
TC (mmol/L) | 4.3 ± 0.8 | 4.4 ± 0.7 | 4.4 ± 0.9 | 0.160 |
LDL (mmol/L) | 2.6 ± 0.7 | 2.7 ± 0.6 | 2.8 ± 0.7 | 0.314 |
HDL (mmol/L) | 1.1 ± 0.4 | 1.0 ± 0.4 | 1.0 ± 0.4 | 0.087 |
GAD(IU/ml) | 119.3 ± 64.8 | 116.0 ± 63.3 | 116.2 ± 65.2 | 0.569 |
ALT (U/L) | 19.2 ± 13.5 | 21.6 ± 13.4 | 21.5 ± 13.9 | 0.645 |
AST (U/L) | 19.4 ± 12.4 | 21.7 ± 13.7 | 21.1 ± 12.9 | 0.626 |
Cr (umol/L) | 61.5 ± 30.7#Δ | 63.6 ± 30.2*Δ | 66.6 ± 30.7*# | 0.021 |
SUA (umol/L) | 318.9 ± 147.7 | 330.6 ± 157.9 | 322.2 ± 155.3 | 0.542 |
HbA1c(%) | 9.2 ± 2.3 | 9.1 ± 2.4 | 9.0 ± 2.5 | 0.057 |
FCP (ng/ml) | 1.4 ± 0.7#Δ | 1.5 ± 0.7*Δ | 1.6 ± 0.7*# | 0.037 |
P2hCP (ng/ml) | 1.8 ± 0.7 | 2.2 ± 0.8 | 2.5 ± 0.8 | 0.068 |
Use of insulin(%) | 76(46.6%)Δ | 75(45.7%) | 73(45.6%)* | 0.229 |
HOMA-IR | 1.6 ± 0.6 | 1.6 ± 0.6 | 1.6 ± 0.6 | 0.468 |
HOMA-β | 12.0 ± 6.3Δ | 13.8 ± 6.1 | 15.2 ± 6.4* | 0.032 |