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Table 2 Clinical characteristics and islet function indexes of total subjects according to GAD values

From: The relationship between red blood cell distribution width and islet β-cell function indexes in patients with latent autoimmune diabetes in adults

 

LADA-1

LADA-2

P

GAD(IU/ml)

≥ 180

< 180

 

n

136

351

 

male (%)

66(48.5%)

164(46.7%)

0.139

Age (years)

58.8 ± 16.3

58.1 ± 15.2

0.741

duration(years)

6.7 ± 4.4

7.0 ± 4.3

0.115

BMI (kg/m2)

19.4 ± 4.3

23.6 ± 4.2

0.034

SBP (mmHg)

127.8 ± 17.3

128.9 ± 18.7

0.259

DBP (mmHg)

70.5 ± 16.7

71.2 ± 18.6

0.395

TG (mmol/L)

1.4 ± 0.7

1.6 ± 0.6

0.017

TC (mmol/L)

4.3 ± 0.8

4.4 ± 0.9

0.085

LDL (mmol/L)

2.6 ± 0.6

2.7 ± 0.7

0.033

HDL (mmol/L)

1.0 ± 0.4

1.0 ± 0.5

0.096

GAD(IU/ml)

272.0 ± 62.7

57.2 ± 54.3

< 0.001

ALT (U/L)

19.7 ± 12.7

21.2 ± 13.6

0.329

AST (U/L)

19.8 ± 13.1

20.5 ± 12.8

0.413

Cr (umol/L)

64.9 ± 30.2

63.5 ± 29.7

0.154

SUA (umol/L)

324.2 ± 145.8

323.7 ± 151.3

0.469

HbA1c(%)

9.4 ± 2.4

9.1 ± 2.1

0.024

FCP (ng/ml)

1.0 ± 0.7

1.7 ± 0.7

0.013

P2hCP (ng/ml)

1.7 ± 0.8

2.4 ± 0.8

0.012

Use of insulin(%)

88(64.7%)

136(38.7%)

< 0.001

HOMA-IR

1.6 ± 0.6

1.7 ± 0.6

0.079

HOMA-β

11.0 ± 5.7

14.7 ± 6.3

0.019

  1. Values are mean ± SD.