Table 3 Summary of meta-regression and stratified analysis of stressful life events and Graves’ disease

Comparison of stressful life events between patients with

9

1.81 (0.01)

0.43 to 3.19

98.0

GD and control groups

Meta-regression of female gender on relation between

9

0.22 (< 0.01)

0.07 to 0.36

stressful life events and GD

Meta-regression of mean age on relation between

9

−0.62 (< 0.01)

−0.80 to−0.43

stressful life events and GD

Stratified analysis by NOS score

0.58 (0.44)

Low-medium (6–7)

5

1.30 (0.09)

−0.22 to 2.81

98.2

Medium-high (8–9)

4

2.46 (0.02)

0.12 to 5.04

99.0

Stratified analysis by Location

0.04 (0.84)

Europe

6

1.71 (0.01)

0.16 to 3.58

98.4

Asia

3

2.01 (0.09)

−0.28 to 4.30

98.9

Stratified analysis by different assessment for

0.13 (0.72)

stressful life events

Semi-structured interviews

3

2.30 (0.23)

−1.49 to 6.09

99.2

Self-rating questionnaires

6

1.57 (0.01)

0.31 to 2.82

98.0

Comparison of stressful life events between not-cured

4

0.32 (0.09)

−0.06 to 0.70

69.0

patients and cured patients with GD after druy therapy