Association of rs2282679 polymorphism in vitamin D binding protein gene (GC) with the risk of vitamin D deficiency in an iranian population: season-specific vitamin D status

Table 2 Characteristics of study participants according to the GC single nucleotide polymorphism rs2282679 genotypes^1,2

	TT (n = 844)	GT (n = 603)	GG (n = 121)	p-value
Age (year)	48.2 (13.3)	49.1 (13.2)	48.6 (13.4)	0.521
Female (%)	50.7	49.4	55.4	0.486
Body mass index (kg/m²)	27.8(4.5)	27.9(4.2)	28.3(4.7)	0.542
Fasting plasma glucose (mg/dl)	98.5(32.9)	101.5(34.8)	101.2(29.9)	0.230
Triglyceride (mg/dl)	148 (105–216)	146 (105–213)	162 (105–235)	0.771
Cholesterol (mg/dl)	213 (44.3)	212 (44.1)	216 (44.3)	0.573
Smoker (%)	29.3	29.9	24.0	0.423
Season of recruitment (%)
Spring	24.8	26.0	28.9	0.196
Summer	30.1	25.9	24.0
Fall	24.2	28.7	30.6
Winter	21.0	19.4	16.5
Vitamin D deficiency (%)	25.2	30.8	30.6	0.049
25-hydroxy vitamin D (ng/ml)	15.5(10–26)	14.0(9.5–25.5)	13.6(8.9–25.8)	0.328

¹Data are presented as mean (SD) or median (25–75 percentile) for quantitative variables according to their distribution and percent for categorical variables
² The alleles of GC rs2282679 are T and G in haploid, and G is the ‘risk’ allele, therefore, the three genotype groups would then be TT, TG and GG.

ISSN: 1472-6823