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Table 1 Basic characteristics of patients with diabetes and controls included in the study

From: Skin advanced glycation end-products as indicators of the metabolic profile in diabetes mellitus: correlations with glycemic control, liver phenotypes and metabolic biomarkers

Variable

Controls (n = 28)

Patients with diabetes mellitus type 1 (n = 30)

Patients with diabetes mellitus type 2 (n = 34)

Age (years)

36.8 (+/− 13.2)

47.5 (+/− 14.4)

62.4 (+/− 11.9)

Males (%)

8 (28.5%)

12 (40%)

20 (58.8%)

BMI (kg/m²)

27.7 (+/− 6.4)

27.8 (+/− 5.5)

36.0 (+/− 10.3)

SAGEs

1.58 (+/− 0.43)

2.11 (+/− 0.52)

2.53 (+/− 0.65)

HbA1c (%)

5.33 (+/− 0.35)

8.10 (+/− 1.17)

7.42 (+/− 1.83)

Cholesterol (mg/dl)

181.7 (+/− 45.2)

179.7 (+/− 33.6)

164.4 (+/− 40.1)

LDL (mg/dl)

117.5 (+/− 33.2)

107.9 (+/− 28.8)

95.2 (+/− 36.4)

Triglycerides (mg/dl)

109.2 (+/− 78.3)

106.8 (+/− 79.0)

159.7 (+/− 113.1)

CAP (dB/m)*

251.5 (+/− 69.6)

240.4 (+/− 62.9)

309.4 (+/− 65.1)

LSM (kPa)*

5.9 (+/− 1.9)

4.7 (+/− 1.4)

9.7 (+/− 5.3)

FGF19 (pg/ml)

179.01 (+/− 116.1)

181.7 (+/− 88.7)

123.1 (+/− 86.1)

FGF21(pg/ml)

235.6 (+/− 322.4)

236.7 (+/− 369.7)

390.4 (+/− 394.7)

GDF15 (pg/ml)

441.7 (+/− 335.2)

1005.4 (+/− 996.9)

1840.2 (+/− 1140.8)

IGF1 (ng/ml)

146.4 (+/− 48.4)

111.6 (+/− 39.9)

120.65 (+/− 43.5)

IGFBP3 (µg/ml)

5.48 (+/− 0.9)

4.1 (+/− 1.2)

4.08 (+/− 1.3)

  1. All results are presented as mean (+/−SD), unless stated otherwise
  2. Abbreviations: BMI: body mass index, CAP: controlled attenuation parameter, dB/m: decibel/meter, FGF19: fibroblast growth factor 19, FGF21: fibroblast growth factor 21, GDF15: growth differentiation factor 15, HbA1c: glycated hemoglobin cluster 1c, IGF1: insulin like growth factor 1, IGFBP3: insulin like growth factor binding protein 3, kPa: kilopascal, LDL: low density lipoprotein, LSM: liver stiffness measurement SAGEs: skin advanced glycation endproducts
  3. *LSM and CAP available for 85 individuals