Table 1 Clinicopathological features of patients underwent EES for pituitary adenoma between with and without nasal irrigation groups (N=173)

Gender

0.464

 Male

88(50.9%)

49

39

 Female

85(49.1%)

52

33

Tumor apoplexy

0.126

 Yes

25(14.5%)

20

5

 No

148(85.5%)

81

67

Preoperative sinusitis

0.819

 Yes

56(32.4%)

32

24

 No

117(67.6%)

69

48

Clival osseous destruction

0.130

 Yes

17(9.8%)

7

10

 No

156(90.2%)

94

62

Extent of tumor resection

0.077

 Total resection

152(87.9%)

85

67

 Subtotal resection

21(12.1%)

16

5

Intraoperative cerebrospinal fluid leak

0.912

 Yes

44(25.4%)

26

18

 No

129(74.6%)

75

54

Postoperative sinusitis

0.418

 Yes

88(50.9%)

54

34

 No

85(49.1%)

47

38

Knosp’s grade

0.065

 Grade 0-2

96(55.5%)

62

34

 Grade 3-4

77(44.5%)

39

38

Hardy’s grade

0.075

 Grade A, B&E

157(90.8%)

95

62

 Grade C-D

16(9.2%)

6

10

Functioning pituitary adenoma

0.077

 Yes

50(28.9%)

24

26

 No

123(71.1%)

77

46

GH secreting adenoma

0.060

 Yes

34(19.7%)

15

19

 No

139(80.3%)

86

53

TBX19

0.233

 positive

47(27.2%)

24

23

 negative

126(72.8%)

77

49

Age (years; mean±SD)

46.78±12.42

45.71±11.90

48.28±13.04

0.181

Maximum diameter (mm; mean±SD)

28.24±10.61

28.35±11.04

28.10±10.06

0.879

Ki-67 index (%;mean±SD)

2.38±1.56

2.56±1.64

2.11±1.40

0.059